Dr. Sheldon Alan Lisker of Lafayette Hill, PA, died peacefully in his home on February 21, 2021 at the age of 88. Born in Philadelphia, PA in 1933 to Dr. Samuel Lisker and Dorothy (nee Amsterdam) Lisker, he graduated from Central High School (Class of 1950), the University of Pennsylvania (Class of 1954) and the University of Pennsylvania School of Medicine (Class of 1958). After completing his one-year medical internship, he served as a physician in the U.S. Air Force from 1959-61 before returning to Philadelphia, where he completed his medical residency and fellowship in 1965. He was an attending physician in Internal Medicine with a specialty in Hematology and Oncology at Graduate Hospital in Philadelphia from 1965-1997. He served as the long-time Chief of Hematology-Oncology and the Co-Director of the Graduate Hospital Cancer Center. In addition, he was a Clinical Professor of Medicine at the University of Pennsylvania School of Medicine for over 25 years, where he received the Dean’s Award for Excellence in Clinical Teaching in 1990.  At the end of his career, he served as a Medical Director of VITAS Hospice from 1995-2009. He was a wonderful and caring physician and mentor who made a lasting impact on his patients, colleagues and students. Sheldon was a lifelong learner who believed in the value of education and passed that on to his four children. He had a passion for classical literature, studying U.S. and European history and listening to classical music and opera. And he was a long-suffering Philadelphia sports fan who was thrilled to see the Eagles finally win the Super Bowl in 2018. In his retirement, he enjoyed reading, traveling and spending quality time with his family and lifelong friends. He is survived by his wife Karen (nee Knapp) of nearly 63 years; his brother Joel (Lena) Lisker of McLean, VA; his four children Gary (Mariam) Lisker of Alexandria, VA, Dr. Susan (Ken) Powell of Olympia, WA, Dr. Donna (Peter) Lisker of Tiverton, RI and Marc (Caroline) Lisker of Greenwich, CT; and his eight grandchildren Chandini, Manisha, Vitthal, Malati, Charlotte, Luke, Olivia and Ethan. Private family service. In lieu of flowers, contributions can be made in his memory to Doctors Without Borders, Partners In Health or the Lisker Family Scholarship Fund at William Penn Charter School.